Targeted Next-Generation Sequencing of a Deafness Gene Panel (MiamiOtoGenes) Analysis in Families Unsuitable for Linkage Analysis

Table 1

Clinical manifestation of the patient cohort with recessive hearing loss.

Family; ID	Individual; ID	Gender	Age of onset; (year)	Mean hearing threshold (dB)		Shape of audiogram	Severity
				Left	Right
R1	II:2	Female	Birth	51	41	High-frequency gently sloping	Moderate
R2	V:1	Male	Birth	74	74	Flat	Moderate
	V:2	Male	Birth	106	100	Flat	Profound
	V:3	Male	Birth	108	104	Flat	Profound
R3	V:3	Female	Birth	106	105	Flat	Profound
R4	IV:1	Male	Birth	112	109	Flat	Profound
	IV:2	Male	Birth	105	104	Flat	Profound
R5	VI:2	Male	Birth	114	114	Flat	Profound
	VI:5	Male	Birth	104	42	Flat	Profound