BioMed Research International / 2018 / Article / Tab 1

Research Article

Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells

Table 1

Cytotoxic activities of steroidal glycosides from S. nigrum on five cancer cell lines.

CompoundsIC50 (M)
A549H1975H1299PANC1MIA-PaCa2

14.9 ± 1.05.5 ± 0.66.3 ± 0.82.9 ± 0.26.4 ± 0.4
2>30>30>30>30>30
3>30>3027.9 ± 3.0>30>30
428.4 ± 3.1>30>30>30>30
Camptothecin1.5 ± 0.90.16 ± 0.10.24 ± 0.14.7 ± 0.53.3 ± 0.2

IC50 values were calculated in a triplicate experiment.
used as positive control.