Linezolid Inhibited Synthesis of ATP in Mitochondria: Based on GC-MS Metabolomics and HPLC Method

<div>PLS-DA score results of rat serum samples: (a) after intragastric administration of linezolid (60, 120 mg/kg, Low, High), control (Class 1), low (Class 2), and high (Class 3); the corresponding load diagram (b). R2Y(cum) = 0.611 and Q2Y(cum) = 0.223.</div>

BioMed Research International

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Figure 4: Linezolid Inhibited Synthesis of ATP in Mitochondria: Based on GC-MS Metabolomics and HPLC Method 