Review Article
Liver Illness and Psoriatic Patients
Table 1
Comparison of liver toxic substances in psoriatic patients.
| | Drug | Potential toxicity | Type of Injury | In hepatic insufficiency | Increased risk |
| | Methotrexate | ↑ | Oxidative stress | NA | NAFLD/Obesity, Leflunomide | | Acitretin | ↑ | Mitochondrial dysfunctions | NA | NA | | TNF inhibitors | ↑ | Autoimmune hepatitis | NA | NA | | IL-12/23 blocker | ↑ | NA | Safe | NA | | IL-17 blockers | NA | NA | NA | NA | | Cyclosporin | Rare | Oxidative stress | Safe | Obesity | | Fructus Psoraleae | ↑ | Liver lipid metabolism | NA | NA |
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NA: not applicable.
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