Research Article

AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway

Table 1

AEG-1, VEGF, and HIF-1α levels in ovarian cancer and normal tissue specimens.

GroupCases
(N)
AEG-1 high expression
n (%)
pVEGF high
expression
n (%)
pHIF-1α high expression
n (%)
p

EOC tissues170107 (62.9)<0.00193 (54.7)<0.001102 (60.0)<0.001
Normal ovary402 (5)4 (10)2 (5)