Adiponectin, Omentin, Ghrelin, and Visfatin Levels in Obese Patients with Severe Obstructive Sleep Apnea

Table 1

Baseline clinical, biochemical, and polysomnographic characteristics of the study subjects.

	Control n=20	OSA n=30	p
Age	36.10±13.67	40.73±8.90	0.192
BMI kg/m^2	27.55±2.97	28.85±2.62	0.108
NC cm	41.55±2.14	43.03±2.05	0.017
WHR	0.92±0.043	0.97±0.06	0.002
MBP	95.72±9.17	100.28±10.59	0.122
FPG mmol/L	5.12±0.73	5.44±0.93	0.202
TC mmol/L	4.80±0.77	5.05±0.93	0.315
TG mmol/L	1.97±2.14	3.31±3.89	0.169
HDL mmol/L	1.08±0.19	1.04±0.19	0.477
LDL mmol/L	3.03±0.74	3.06±0.76	0.909
hsCRP mg/L	1.19±1.14	2.09±1.80	0.036
AHI	1.93±1.38	61.48±15.00	<0.001
Mean SpO2,%	95.55±1.24	91.40±4.55	<0.001
Min SpO2, %	89.85±3.44	71.77±11.45	<0.001
SpO2<90%, %	0.09±0.14	23.46±20.17	<0.001
REM, %	15.47±8.06	13.55±6.06	0.343
NREM, %	76.31±8.51	79.18±11.13	0.333
N1, %	9.18±7.06	7.30±5.71	0.307
N2, %	54.12±7.84	66.32±12.18	<0.001
N3, %	13.02±7.65	5.57±5.69	<0.001
ESS	7.90±4.48	11.10±5.35	0.032

BMI: body mass index, NC: neck circumference, WHR: waist-hip ratio, MBP: mean blood pressure, FPG: fasting plasma glucose, TC: total Cholesterol, TG: triglycerides, HDL: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol, hsCRP: hypersensitive respective Protein. AHI: apnea-hypopnea index, Mean SpO₂: average SpO₂, Min SpO₂: minimum SpO₂, SpO₂<90%: percentage of total sleep time spent with SpO₂<90%, REM: percentage of rapid eye movement sleep in total sleep time, NREM: percentage of rapid eye movement sleep in total sleep time, N1, N2, N3: percentage of stage N1, stage N2, and stage N3 in total sleep time, and ESS: Epworth sleepiness scale.