Clinical Study

The Impact of Artesunate-Amodiaquine on Schistosoma mansoni Infection among Children Infected by Plasmodium in Rural Area of Lemfu, Kongo Central, Democratic Republic of the Congo

Table 1

General characteristics of study participants.

Variablesn (%) IC 95%Mean ±SDMedian (IQ)Range

Total effectif364
Weight (Kg)18.5 (15.5-23)9-54
Age (years)7.7±3.23-15
Sex
Female164 (45.1)39.8-50.3
Male200 (54.9)49.6-60.1
Age groups (years)
3 - 5120 (33.0)28.2-38.1
6-9140 (38.5)33.4-43.6
10-15104 (28.5)24.-33.6
School level of parents/guardians
No instruction8 (2.2)1.0-4.4
Primary140 (38.7)33.7-43.9
Secondary209 (57.7)52.5-62.8
University5 (1.4)0.5-3.3
Profession of parents/guardians
Mechanic1 (0.3)0.01-1.6
Agriculture351 (96.4)93.8-98.0
Teaching9 (2.5)1,21-4,81
Commerce3 (0.8)0.2-2.5
Taking praziquantel during last campaign24 (6.6)4.3-9.8
Histories of symptoms two weeks before and clinic signs
History of fever180(49.4)44.2-54.7
Abdominal pain134(36.8)31.8-42.0
Melaena117(32.1)27.4-37.2
Headache85(23.3)19.2-28.1
Diarrhea42(11.5)8.5-15.3
Vomiting27(7.4)5.0-10.7
Anorexia3(0.8)0.2-2.6
Haematuria2(0.5)0.1-2.2
Cough5(1.3)2.0-6.1
Vertigo1(0.2)0.01-1.7
Mictalgie9(2.4)1.2-4.8
Skin rash13(3.5)2.0-6.1
Hepatomegaly132(36.5)31.3-41.4
Splenomegaly152(41.7)36.6-47.0
Use of bednet last night64 (17.6)13.8-21.9
Parasitic infections
Plasmodium spp.303(83.2)78.9-86.8
S. mansoni218(59.8)54.6-64.9
A. lumbricoides8(2.2)1.0-4.4
T. trichuris5(1.3)0.5-3.3
Co-infection malaria + Schistosomiasis171(46.9)41.6-52.2
Malaria PD(trophozoites//µl)380(320-800)40-34000
S. mansoni eggs load(eggs /g of feces)192(60-612)24-8760
S. mansoni infection intensities
Light82(37.6)31.1-44.4
Moderate63(28.9)22.9-35.4
Severe73(33.5)27.2-40.1
Anaemia 235(64.6)59.3-69.4
Anaemia intensities
Light132(56.2)49.5-62.6
Moderate99(42.1)35.7-48.7
Severe4(1.7)0.4-4.3
Hb (g/dl)10.8±1.43.8-15.5