Enhancement of Immunoregulatory Function of Modified Bone Marrow Mesenchymal Stem Cells by Targeting SOCS1

<div><i>Changes in BM-MSCs miR-155 levels affect T cell-specific transcription factors</i>. (a) miR-155 expression in BM-MSCs was blocked by inhibitor treatment. (b) Alterations of<i> Tbx21</i>,<i> Gata3,</i> and<i> Rorc</i> mRNA levels of SMCs following miR-155 inhibition in BM-MSCs. (c) Overexpression of miR-155 in BM-MSCs. (d) The effects of miR-155 overexpression on Tbx21, Gata3, and Rorc mRNA levels of SMCs. 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BioMed Research International

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Figure 3

Figure 3: Enhancement of Immunoregulatory Function of Modified Bone Marrow Mesenchymal Stem Cells by Targeting SOCS1 