Cinnamaldehyde Improves Lifespan and Healthspan in Drosophila melanogaster Models for Alzheimer’s Disease

Figure 6

The effect of training on courtship behavior in AD flies overexpressing either MAPT or Aβ₄₂. The courtship index was significantly decreased after training in flies fed control diet ((a) and (c)), and 80 mM cinnamaldehyde ((b) and (d)) of both fly models for AD with overexpression of MAPT or Aβ₄₂. ((a). P = 0.04, naïve n = 46, trained n = 44; (b). P = 0.002; naïve n = 40, trained n = 48; (c). P = 0.04; naïve n = 42, trained n = 46; (d). P = 0.03; naïve n = 45, trained n = 44)_.

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