Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics

Figure 2

Volcano plot showing the aberrantly expressed genes between the ABC and GCB samples. Red dots indicate the genes showing an expression difference with a |log2 FC|>1 and p < 0.05, while the black dots fail to meet these criteria. The ABC-upregulated DEGs are displayed on the left of the plot, and the downregulated DEGs are on the opposite side. Hub genes and some genes with highest adjust p value and |log2 FC| value were marked in the figure. The x-axis represents the log2 FC score, and the y-axis shows the –log10 value ( value). This volcano plot was generated using R language (R 3.4.0).