Research Article

Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics

Table 3

Significantly enriched pathway terms for DEGs in DLBCL. Functional and signaling pathway enrichment analyses of the DEGs were conducted using the DAVID website.

TermKEGG PathwayCountP ValueGenes

hsa05202Transcriptional misregulation in cancer70.00014NFKBIZ, FUT8, LMO2, CCND2, BCL2A1, ETV6, CDK14
hsa04672Intestinal immune network for IgA production40.001522437CCR10, TNFRSF13B,
AICDA, HLA-DOB
hsa05340Primary immunodeficiency30.011947217TNFRSF13B, AICDA, BLNK
hsa04640Hematopoietic cell lineage30.06510351IL2RA, CD44, MME
hsa04064NF-kappa B signaling pathway30.067811577CFLAR, BCL2A1, BLNK
hsa00533Glycosaminoglycan biosynthesis - keratan sulfate20.071387272FUT8, CHST2