Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis

Figure 4

A. villosum protected the intestinal mucosal barrier and reduced the effects of endotoxins. (a) Comparison of microscopic morphology in ileum tissue among CON, MOD, EZE, WEAV.M, VOAV.M, and BA.M groups. Sectional representations (100× magnification, hematoxylin and eosin stain) of ileum tissues are shown. Degeneration and necrosis of ileum were relieved after VOVA and BA treatment. (b) Concentrations of ZO-1 and occludin. (c) Concentrations of LPS in hepatic portal vein. LPS levels in hepatic portal vein blood samples were measured using a tachypleus amebocyte lysate test (mean ± SD, n = 10). Statistical significance: versus model; versus model; < 0.001 versus model.

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