Novel Intravaginal Drug Delivery System Based on Molecularly PEGylated Lipid Matrices for Improved Antifungal Activity of Miconazole Nitrate

Figure 1

DSC thermograms of Softisan® 154, PEG 4000, optimized PEGylated and non-PEGylated lipid matrices (representative batch) in superposition. Key: 1 = PEG-LM, 2 = LM, 3 = Softisan® 154, and 4 = PEG 4000, and LM means lipid matrix prepared with super-refined sunseed oil and Softisan® 154, while PEG-LM means PEGylated lipid matrix made with LM and PEG 4000.