Research Article

Effects of Juniperus phoenicea Hydroalcoholic Extract on Inflammatory Mediators and Oxidative Stress Markers in Carrageenan-Induced Paw Oedema in Mice

Table 6

Effects of J. phoenicea EtOH-H2OE and dexamethasone on CAT, SOD, GPx, and MDA activities in carrageenan-induced paw oedema.

TreatmentMDA
(nmol /mg protein)
SOD
(units/mg protein)
CAT
(mol H2O2/min/mg protein)
GPx
(mol GSH/mg protein)

Control1.08 ± 0.07 ###8.44 ± 0.31###186.04± 6.13###5.6± 1.07 ###
Carr1.94± 0.012.26 ± 0.1277.12± 1.61.23± 0.07
Carr + DEX0.98 ± 0.04 ###6.65 ± 0.57 ###114.13± 3.94.36 ± 0.19 ###
Carr + J. phoenicea EtOH-H2OE1.03 ± 0.009 ###7.11 ± 0.13 ###169.62± 4.3##4.44 ± 0.31 ###

Values are mean ± SE for six rats in each group. represents P < 0.001; represents P < 0.01; represents P < 0.05.
SOD: superoxide dismutase, CAT: catalase, GSH: glutathione peroxidase, MDA: malondialdehyde.
(P < 0.001) represents highly significant difference in comparison with control mice.
(P < 0.01) represents moderately significant difference in comparison with control mice.
(P <0.05) represents significant difference in comparison with control mice.
(P <0.001) represents highly significant difference in comparison with Carr group.
(P < 0.01) represents moderately significant difference in comparison with Carr group.