In Vivo Study on Analgesic, Muscle-Relaxant, Sedative Activity of Extracts of Hypochaeris radicata and In Silico Evaluation of Certain Compounds Present in This Species

Table 2

(a) Phytochemical composition of crude extract and various fractions of H. radicata, where the signs (+) and (−) represent the presence and absence, respectively.

Phytochemicals	Crude extract	n-Hexane fraction	Chloroform fraction	Ethyl acetate fraction
Alkaloids	+	−	+	+
Anthraquinones	−	−	−	+
Tannins	+	−	+	+
Glycosides	+	+	+	+
Reducing sugars	+	−	−	+
Saponins	+	−	−	+
Flavonoids	+	−	−	+
Phlobatannins	+	−	−	+
Steroids	+	+	+	+
Terpenoids	+	+	+	+
Coumarin	−	−	−	−
Emodin	−	−	−	−
Anthocyanin	−	−	−	−

(b) Identification of total phenolic contents of crude extract and various fractions of H. radicata

Phytochemicals	Crude extract	n-Hexane fraction	Chloroform fraction	Ethyl acetate fraction
Total phenolic contents (GAE)	19.17	9.36	8.15	11.73
SD	2.85	1.57	2.48	2.08