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BioMed Research International
/
2018
/
Article
/
Tab 4
/
Research Article
In Vivo Study on Analgesic, Muscle-Relaxant, Sedative Activity of Extracts of
Hypochaeris radicata
and In Silico
Evaluation
of Certain Compounds Present in This Species
Table 4
Acute toxicity of crude extract and its fractions of
H. radicata
.
Treatment
Dose (mg/kg)
No. of animals died/5
% mortality
Normal saline
10 ml/kg
0/5
0
Crude extract
250
0/5
0
500
0/5
0
1000
0/5
0
n-Hexane fraction
250
0/5
0
500
0/5
0
1000
0/5
0
Chloroform fraction
250
0/5
0
500
0/5
0
1000
0/5
0
Ethyl acetate fraction
250
0/5
0
500
0/5
0
1000
0/5
0