Research Article

In Vivo Study on Analgesic, Muscle-Relaxant, Sedative Activity of Extracts of Hypochaeris radicata and In Silico Evaluation of Certain Compounds Present in This Species

Table 4

Acute toxicity of crude extract and its fractions of H. radicata.

TreatmentDose (mg/kg)No. of animals died/5% mortality

Normal saline10 ml/kg0/50

Crude extract2500/50
5000/50
10000/50

n-Hexane fraction2500/50
5000/50
10000/50

Chloroform fraction2500/50
5000/50
10000/50

Ethyl acetate fraction2500/50
5000/50
10000/50