Research Article

Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study

Table 1

Demographic and clinical characteristics of the study population.

CharacteristicsPH patients
()

Age, years50.4 ± 13.7
Gender, (%)
 Female37 (75.5)
 Male12 (24.5)
Marital status, (%)
 Single11 (22.4)
 Married/divorced/widowed38 (77.6)
Working status, (%)
 Full-time15 (34.7)
 Homemaker9 (18.4)
 Retired23 (46.9)
Disease duration, months57.1 ± 58.8
PH aetiology, (%)
 PAH and others37 (75.5)
 CTEPH12 (24.5)
Comorbidities, (%)
 Yes28 (57.1)
 No21 (42.9)
WHO Functional class, (%)
 I/II34 (69.4)
 III/IV15 (30.6)
6MWD, meters428.0 ± 105.8
Borg dyspnea2.2 ± 2.6
HR_Bas, bpm78.2 ± 11.6
HR_Max, bpm107.9 ± 19.1
SBP, mmHg113.4 ± 17.7
DBP, mmHg68.2 ± 13.6
O2Sat_Bas, mmHg94.0 ± 3.4
O2Sat_Min, mmHg80.5 ± 15.1
NT-proBNP, pg/mL684.6 ± 908.4
RAP, mmHg7.1 ± 4.6
mPAP, mmHg44.8 ± 18.2
PAOP, mmHg9.8 ± 4.1
CI, L/min/m23.1 ± 0.9
PVR, Wood units7.0 ± 4.3
Diuretics, (%)
 Yes29 (59.2)
 No20 (40.8)
Oral anticoagulants, (%)
 Yes24 (49.0)
 No25 (51.0)
Calcium channel blockers, (%)
 Yes5 (10.2)
 No44 (89.8)
Oxygen therapy, (%)
 Yes20 (40.9)
 No29 (59.1)
PH specific therapy, (%)
 Monotherapy23 (46.9)
 Combination therapy20 (40.8)
 No therapy6 (12.2)
PH specific therapy route, (%)
 Oral36 (73.5)
 Parenteral7 (14.3)

Data displayed as mean ± SD, except when otherwise indicated; 6MWD: 6-minute walk distance; NT-proBNP: N-terminal pro-brain natriuretic peptide; Borg: Borg dyspnea score; CI: cardiac index; CTEPH: chronic thromboembolic pulmonary hypertension; DBP: diastolic blood pressure; HR_Bas: baseline heart rate; HR_Max: maximum heart rate; mPAP: mean pulmonary arterial pressure; PAH: pulmonary arterial hypertension; PAOP: pulmonary artery occlusion pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; O2Sat_min: minimum oxygen saturation; O2Sat_bas: baseline oxygen saturation; SBP: systolic blood pressure. therapy: CTEPH patients waiting for surgical treatment ; Porto-pulmonary hypertension waiting for liver transplantation . Low risk congenital heart disease , and idiopathic PAH before specific therapeutic introduction .