URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion

Figure 6

Overexpression of URG11 increases the growth, migration, and invasion of prostate cancer cells. URG11 overexpression plasmid was constructed and transfected into LNCaP cells. The protein expression levels were determined by western blot (a) and the statistical analysis of relative fold changes was shown in (b). The growth rate of LNCaP cells was determined by MTS assay (c) and the proliferation rate was determined by wound healing assay (d). Transwell system was applied to test the migration and invasion ability of URG11 overexpressed cells and the data were shown in (e) and (f). Mean ± SD. denotes p < 0.05 versus Vector control group.

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