Testing Pathological Variation of White Matter Tract in Adult Rats after Severe Spinal Cord Injury with MRI

Table 1

Summary of the temporal changes at lesion core in FA, MD, AD, and RD for the various ROIs.

ROI	DC
DTI parameters	FA		MD		AD		RD
	mean	s.e.m	mean	s.e.m	mean	s.e.m	mean	s.e.m
Pre-injured	0.81	0.02	0.81	0.01	1.85	0.01	0.29	0.01
SCI 1d	0.31	0.02	0.64	0.03	0.78	0.06	0.56	0.02
SCI 3d	0.28	0.01	0.65	0.04	0.76	0.06	0.59	0.05
SCI 7d	0.29	0.01	0.70	0.05	0.94	0.09	0.58	0.03
SCI 14d	0.29	0.01	0.73	0.03	1.02	0.07	0.58	0.01
ROI	LLWM
DTI parameters	FA		MD		AD		RD
	mean	s.e.m	mean	s.e.m	mean	s.e.m	mean	s.e.m
Pre-injured	0.79	0.02	0.79	0.01	1.79	0.01	0.30	0.01
SCI 1d	0.50	0.01	0.62	0.02	1.09	0.05	0.38	0.02
SCI 3d	0.45	0.01	0.67	0.03	1.07	0.11	0.46	0.02
SCI 7d	0.46	0.01	0.71	0.03	1.16	0.10	0.48	0.02
SCI 14d	0.47	0.01	0.69	0.03	1.15	0.08	0.45	0.01
ROI	RLWM
DTI parameters	FA		MD		AD		RD
	mean	s.e.m	mean	s.e.m	mean	s.e.m	mean	s.e.m
Pre-injured	0.80	0.02	0.79	0.01	1.79	0.02	0.30	0.02
SCI 1d	0.49	0.01	0.62	0.02	1.09	0.04	0.39	0.03
SCI 3d	0.45	0.01	0.68	0.04	1.08	0.08	0.46	0.04
SCI 7d	0.45	0.01	0.70	0.03	1.13	0.09	0.48	0.03
SCI 14d	0.46	0.01	0.70	0.02	1.18	0.05	0.47	0.02
ROI	LVWM
DTI parameters	FA		MD		AD		RD
	mean	s.e.m	mean	s.e.m	mean	s.e.m	mean	s.e.m
Pre-injured	0.78	0.02	0.83	0.02	1.81	0.02	0.33	0.02
SCI 1d	0.50	0.02	0.62	0.02	1.11	0.03	0.38	0.02
SCI 3d	0.46	0.02	0.69	0.01	1.10	0.03	0.49	0.03
SCI 7d	0.47	0.02	0.65	0.03	1.01	0.10	0.47	0.03
SCI 14d	0.48	0.01	0.64	0.02	1.02	0.06	0.45	0.01
ROI	RVWM
DTI parameters	FA		MD		AD		RD
	mean	s.e.m	mean	s.e.m	mean	s.e.m	mean	s.e.m
Pre-injured	0.78	0.02	0.82	0.02	1.82	0.02	0.31	0.02
SCI 1d	0.51	0.02	0.61	0.02	1.09	0.04	0.37	0.03
SCI 3d	0.47	0.02	0.69	0.04	1.10	0.12	0.48	0.02
SCI 7d	0.48	0.02	0.71	0.03	1.14	0.10	0.49	0.02
SCI 14d	0.50	0.01	0.67	0.02	1.13	0.05	0.44	0.01

P < 0.05, P < 0.01, and P < 0.001.