The Effect of 5-Hydroxytryptamine Receptor Antagonist in Preventing Pain/Limb Shrinkage Reaction Associated with Rocuronium Injection

Table 1

Characteristics and Jadad scores of the included studies in the meta-analysis.

Author (Published year)	Country	Headcount	Grouping (dose regimen)	Surgical setting	Application time
Reddy 2001	Singapore	60	Normal Saline; Ondansetron 4 mg; Lidocaine 50mg	elective orthopaedic and gastrointestinal procedures	One minute after the administration
Memis 2002	Turkey	250	Normal Saline; Ondansetron 4 mg; Lidocaine 30mg; Tramadol 50 mg; Fentanyl 0.1mg	Elective hysteroscopy or arthroscopy operations	After 20 s
Wang 2010	China	120	Normal Saline 2ml; Lidocaine 20mg; Ondansetron 4 mg; Ondansetron 4 mg+Lidocaine 20mg	Laparoscopic surgery	One minute after the administration
Cho 2014	Korea	80	Normal Saline; Ondansetron 4 mg	Elective surgery	Thirty seconds after the injection
Kuang 2014	China	200	Normal Saline; palonosetron 0.25mg; Lidocaine 40mg; palonosetron 0.25mg+Lidocaine 40mg	Elective surgery	Thirty seconds after the injection
Xu 2015	China	200	Normal Saline 2ml; troposetron 5 mg; Dezocine 5mg; Troposetron 5mg+Dezocine 5mg	Elective surgery	Two minute after the administration
Park 2016	Korea	120	Normal Saline 2ml; Lidocaine 20mg; palonosetron 0.075 mg	Laparoscopic surgery	Two minutes after the administration