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BioMed Research International
Volume 2018, Article ID 4280792, 6 pages
https://doi.org/10.1155/2018/4280792
Research Article

Asthma and Seroconversion from Toxocara spp. Infection: Which Comes First?

1Departamento de Saúde Coletiva, Faculdade de Ciências Médicas, Campinas, SP, Brazil
2Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, Laboratório de Imunopatologia da Esquistossomose (LIM 06), São Paulo, SP, Brazil

Correspondence should be addressed to Paula Mayara Matos Fialho; moc.liamg@2arayamaluap

Received 17 November 2017; Revised 9 February 2018; Accepted 8 April 2018; Published 14 May 2018

Academic Editor: Sara L. Zimmer

Copyright © 2018 Paula Mayara Matos Fialho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to estimate the incidence of seroconversion of Toxocara spp. infection and related variables. We conducted a cohort study of 77 children aged 2–12 years who had negative serology in a previous cross-sectional study. Univariate and bivariate analyses were performed to describe the cohort, using socioeconomic, behavioral, and health conditions as variables. Logistic regression analysis was performed using seroconversion as the dependent variable, and the remaining variables are treated as independent variables. Asthma was the only independent variable that showed an association with seroconversion, with an odds ratio = 3.57 (1.01–12.6). The incidence of seroconversion from Toxocara spp. infection in the children followed was 10.4 per 100 per year. Previous studies reporting an association of asthma with toxocariasis have only been carried out using cross-sectional studies. Therefore, this study is one of only a few describing the incidence of seroconversion from Toxocara spp. infection, which is relevant for understanding the burden of this parasite.