Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis

Figure 2

Echo-Doppler parameters in Wt and TLR9^-/- mice 8 hr. after CLP. Heart rate (a), left ventricular (LV) stroke volume (b), cardiac output (c), LV ejection fraction (d), isovolumic relaxation time (e), peak E’ velocity from the septal annulus, E′sa (f), peak E’ velocity from the lateral annulus, E’la (g), and LV volume diastole (h) represent selected measures of systolic and diastolic heart function in mice before and 8 hr. after CLP. For each bar, n = 5 mice. n.s., nonsignificant.

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