Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma
Effect of Rg3 on Akt phosphorylation and expression levels of Bax, Bcl-2, and caspase in human osteosarcoma cells. (a) Total protein from whole cell lysates was extracted to analyze Bcl2, caspase 3, PI3K, pAkt, and mTOR assessed by Western blotting. (b) Reverse transcription-quantitative polymerase chain reaction analysis of Bcl2, caspase3, caspase9, and BAX mRNA expression levels in osteosarcoma cells. Data are presented as the mean ± SD. ..