BioMed Research International / 2018 / Article / Fig 4

Research Article

Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-κB Activation in Human Myeloid Leukemia THP-1 Cells

Figure 4

Inhibition of Hsp90 reduces TLR5 cell surface expression. Cell surface expression of TLR5 in THP-1 cells was examined by flow cytometry analysis. THP-1 cells were treated with or without the Hsp90 inhibitors, (a) GA, (b) 17-AAG, and (c) radicicol at various concentrations for 24 h. Relative fluorescence intensity was measured, and data are expressed as means of relative expression ratio ± SD (). versus DMSO- or MeOH-treated group.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.