Review Article

The Role of Actin Dynamics and Actin-Binding Proteins Expression in Epithelial-to-Mesenchymal Transition and Its Association with Cancer Progression and Evaluation of Possible Therapeutic Targets

Figure 3

Main changes in -catenin and E-cadherin expression during EMT and MET with possible therapeutic targets. During EMT process β-catenin expression pattern changes from cytoplasmatic to nuclear; simultaneously E-cadherin is downregulated and vimentin is upregulated. After MET process occurs expression pattern again turns to epithelial.