Research Article

Beneficial Effects of Concentrated Growth Factors and Resveratrol on Human Osteoblasts In Vitro Treated with Bisphosphonates

Table 3

Human osteoblast (HOB) treatments in mineralization medium (OMM) for 21 days.

Cell treatments—21 daysEvaluation performed

Osteoblast mineralization medium (OMM)—controlAlizarin Red S staining
ELISA for
osteoprotegerin (OPG) and bone morphogenetic protein-2 (BMP-2)
OMM + RSV 10 µM (OMM + R10)
OMM + AL 5 µM (OMM + AL5)
OMM + ZOL 5 µM (OMM + ZOL5)
OMM + AL 5 µM +RSV 10 µM (OMM + AL5 + R10)
OMM + ZOL 5 µM +RSV 10 µM (OMM + ZOL5 + R10)
OMM + CGF(OMM + CGF)
OMM + CGF + RSV 10 µM (OMM + CGF + R10)
OMM + CGF + AL 5 µM (OMM + CGF + AL5)
OMM + CGF + ZOL 5 µM (OMM + CGF + ZOL5)
OMM + CGF + RSV 10 µM + AL 5 µM (OMM + CGF + R10 + AL5)
OMM + CGF + RSV 10 µM + ZOL 5 µM (OMM + CGF + R10 + ZOL5)