Research Article

Guava Leaf Extract Diminishes Hyperglycemia and Oxidative Stress, Prevents β-Cell Death, Inhibits Inflammation, and Regulates NF-kB Signaling Pathway in STZ Induced Diabetic Rats

Table 2

Tissue enzymatic antioxidant status of the control and experimental rats.

GroupsControlGLE
control
DiabeticD + GLE
(200 mg/kg b.w.)
D + GB
(600 μg/kg b.w.)

SOD (50% NBT reduction/min/mg protein)
 Liver
 Kidney
 Pancreas

CAT (μmoles of H2O2 utilized/min/mg protein)
 Liver
 Kidney
 Pancreas

GPx (μmoles of GSH utilized/min/mg protein)
 Liver
 Kidney
 Pancreas

GR (μmoles of NADPH oxidized/min/mg protein)
 Liver
 Kidney
 Pancreas

GLE: guava leaf extract. Values are given as means ± SD for six rats in each group. Group (group 2) with no significant difference compared to control group. Significantly different from control group at . Significantly different from diabetic group at . Duncan’s Multiple Range Test (DMRT).