Research Article
MicroRNA-219-5p Promotes Tumor Growth and Metastasis of Hepatocellular Carcinoma by Regulating Cadherin 1
Table 2
Univariate and multivariate analyses of factors associated with overall survival (OS) inpatients with hepatocellular carcinoma (HCC).
| Features | Overall survival | Univariate | Multivariate | HR | 95% CI | |
| Sex | | | | | Male versus female | 0.537 | | | NA | Age | | | | | >50 versus ≤50 | 0.404 | | | NA | HBsAg | | | | | Positive versus negative | 0.112 | | | NA | AFP | | | | | 20 ng/ml versus ≤20 ng/ml | 0.069 | | | NA | Liver cirrhosis | | | | | Yes versus no | 0.307 | | | NA | Tumor size | | | | | >5 cm versus ≤5 cm | <0.001 | 2.620 | 1.675~4.099 | <0.001 | Tumor encapsulation | | | | | Yes versus no | 0.017 | 1.084 | 0.666~1.764 | 0.746 | Tumor number | | | | | Multiple versus single | 0.065 | | | | Vascular invasion | | | | | Yes versus no | 0.001 | 1.833 | 1.179~2.848 | 0.007 | Tumor differentiation | | | | | I~II versus III~IV | 0.113 | | | | miR-219-5p | | | | | High versus low | 0.007 | 1.689 | 1.433~3.903 | 0.036 |
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