Monoamine Oxidase-A Inhibition and Associated Antioxidant Activity in Plant Extracts with Potential Antidepressant Actions

Figure 5

Inhibition of human monoamine oxidase-A (MAO-A) by P. harmala seed (a) and L. meyenii root (maca) extracts (b) (capsules, ▼ and powder, ■). (c) HPLC chromatogram of P. harmala seed extract which potently inhibited human MAO-A. Absorbance detection at 254 nm. Compounds identified are harmaline (m/z at 215 (M + H)⁺, at 375 nm) and harmine (m/z at 213 (M + H)⁺, at 245 and 322 nm).

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(b)

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