Research Article

Spectral CT Analysis of Solitary Pulmonary Nodules for Differentiating Malignancy from Benignancy: The Value of Iodine Concentration Spatial Distribution Difference

Table 2

Quantitative assessment of IC and standard deviation of iodine concentration in PP, AP, and VP.

GroupdNIC

PP
 Malignant nodules(0.67,0.41, 1.19)(0.43, 0.22, 0.64)(0.31, 0.11, 0.57)
 Benign nodules(0.38, 0.19, 0.82)(0.53,0.36,1.29)(-0.26, -0.5, -0.1)
 P value0.0370.093p≤0.001
AP
 Malignant nodules0.283 ±0.1650.190 ±0.1170.093 ±0.094
 Benign nodules0.183 ±0.0810.258 ±0.094-0.075 ±0.060
 P value0.0120.024p≤0.001
VP
 Malignant nodules0.577±0.1990.406±0.1420.171±0.137
 Benign nodules0.407±0.2470.591±0.247-0.183±0.127
 P value0.0050.004p≤0.001

PP, pulmonary phase; AP, arterial phase; VP, venous phase; , normalized iodine concentration in the proximal region; , normalized iodine concentration in the distal region; dNIC, -.