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BioMed Research International
Volume 2018, Article ID 5326340, 13 pages
https://doi.org/10.1155/2018/5326340
Clinical Study

Peri-Implant Bone Resorption during Healing Abutment Placement: The Effect of a 0.20 Chlorhexidine Gel vs. Placebo—A Randomized Double Blind Controlled Human Study

University G. d’Annunzio Chieti-Pescara, Department of Medical Oral and Biotechnological Sciences, Via dei Vestini 31, 66100 Chieti (CH), Italy

Correspondence should be addressed to Bruna Sinjari; ti.hcinu@irajnis.b

Received 13 August 2018; Revised 23 September 2018; Accepted 27 September 2018; Published 16 October 2018

Academic Editor: Konstantinos Michalakis

Copyright © 2018 Bruna Sinjari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. S. Pikner, K. Gröndahl, T. Jemt, and B. Friberg, “Marginal Bone Loss at Implants: A Retrospective, Long-Term Follow-Up of Turned Brånemark System® Implants,” Clinical Implant Dentistry and Related Research, vol. 11, no. 1, pp. 11–23, 2009. View at Publisher · View at Google Scholar
  2. P. Simonis, T. Dufour, and H. Tenenbaum, “Long-term implant survival and success: a 10-16-year follow-up of non-submerged dental implants,” Clinical Oral Implants Research, vol. 21, no. 7, pp. 772–777, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. C. E. Misch, M. L. Perel, H.-L. Wang et al., “Implant success, survival, and failure: the international congress of oral implantologists (ICOI) pisa consensus conference,” Implant Dentistry, vol. 17, no. 1, pp. 5–15, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Berglundh, L. Persson, and B. Klinge, “A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years,” Journal of Clinical Periodontology, vol. 29, 3, pp. 197–212, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Oh, J. Yoon, C. E. Misch, and H. Wang, “The causes of early implant bone loss: myth or science?” Journal of Periodontology, vol. 73, no. 3, pp. 322–333, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. T. O. Albrektsson, C. B. Johansson, and L. Sennerby, “Biological aspects of implant dentistry: osseointegration,” Periodontology 2000, vol. 4, no. 1, pp. 58–73, 1994. View at Publisher · View at Google Scholar · View at Scopus
  7. J. H. Fu, Y. T. Hsu, and H. L. Wang, “Identifying occlusal overload and how to deal with it to avoid marginal bone loss around implants,” European Journal of Oral Implantology, vol. 5, no. 1, pp. 91–103, 2012. View at Google Scholar
  8. N. P. Lang, T. Berglundh, and Working Group 4 of the Seventh European Workshop on Periodontology, “Periimplant diseases: where are we now?—consensus of the Seventh European Workshop on Periodontology,” Journal of Clinical Periodontology, vol. 38, no. 11, pp. 178–181, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Berardini, P. Trisi, B. Sinjari, A. W. S. Rutjes, and S. Caputi, “The effects of high insertion torque versus low insertion torque on marginal bone resorption and implant failure rates: A systematic review with meta-analyses,” Implant Dentistry, vol. 25, no. 4, pp. 532–540, 2016. View at Publisher · View at Google Scholar · View at Scopus
  10. R. E. Jung, A. Zembic, B. E. Pjetursson, M. Zwahlen, and D. S. Thoma, “Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years,” Clinical Oral Implants Research, vol. 23, no. 6, pp. 2–21, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. J. S. Hermann, D. Buser, R. K. Schenk, and D. L. Cochran, “Crestal bone changes around titanium implants. A histometric evaluation of unloaded non-submerged and submerged implants in the canine mandible,” Journal of Periodontology, vol. 71, no. 9, pp. 1412–1424, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Berglundh and J. Lindhe, “Dimension of the periimplant mucosa. Biological width revisited,” Journal of Clinical Periodontology, vol. 23, no. 10, pp. 971–973, 1996. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Albrektsson, GA. Zarb, P. Worthington, and A. R. Erikson, “The long-term efficacy of current used dental implants: a review and proposed criteria of success,” The International Journal of Oral & Maxillofacial Implants, vol. 1, pp. 11–25, 1986. View at Google Scholar
  14. D. E. Smith and G. A. Zarb, “Criteria for success of osseointegrated endosseous implants,” The Journal of Prosthetic Dentistry, vol. 62, no. 5, pp. 567–572, 1989. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Broggini, L. M. McManus, J. S. Hermann et al., “Peri-implant inflammation defined by the implant-abutment interface,” Journal of Dental Research, vol. 85, no. 5, pp. 473–478, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. D. S. M. De Castro, M. A. R. De Araujo, C. A. M. Benfatti et al., “Comparative histological and histomorphometrical evaluation of marginal bone resorption around external hexagon and morse cone implants: An experimental study in dogs,” Implant Dentistry, vol. 23, no. 3, pp. 270–276, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. D. P. Callan, A. O'Mahony, and C. M. Cobb, “Loss of crestal bone around dental implants: A retrospective study,” Implant Dentistry, vol. 7, no. 4, pp. 258–266, 1998. View at Publisher · View at Google Scholar · View at Scopus
  18. A. G. Dellow, C. H. Driessen, and H. J. C. Nel, “Scanning electron microscopy evaluation of the interfacial fit of interchanged components of four dental implant systems,” International Journal of Prosthodontics, vol. 10, no. 3, pp. 216–221, 1997. View at Google Scholar · View at Scopus
  19. D. Tripodi, G. Vantaggiato, A. Scarano et al., “An in vitro investigation concerning the bacterial leakage at implants with internal hexagon and Morse taper implant-abutment connections,” Implant Dentistry, vol. 21, no. 4, pp. 335–339, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. S. D'Ercole, D. Tripodi, L. Ravera, V. Perrotti, A. Piattelli, and G. Iezzi, “Bacterial leakage in morse cone internal connection implants using different torque values: An in vitro study,” Implant Dentistry, vol. 23, no. 2, pp. 175–179, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Scarano, V. Perrotti, A. Piattelli, F. Iaculli, and G. Iezzi, “Sealing capability of implant-abutment junction under cyclic loading: A toluidine blue in vitro study,” Journal of Applied Biomaterials and Functional Materials, vol. 13, no. 3, pp. e293–e295, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. C. M. Schmitt, G. Nogueira-Filho, H. C. Tenenbaum et al., “Performance of conical abutment (Morse Taper) connection implants: a systematic review,” Journal of Biomedical Materials Research Part A, vol. 102, no. 2, pp. 552–574, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. I. Ericsson, L. G. Persson, T. Berglundh, C. P. Marinello, J. Lindhe, and B. Klinge, “Different types of inflammatory reactions in peri-implant soft tissues,” Journal of Clinical Periodontology, vol. 22, no. 3, pp. 255–261, 1995. View at Google Scholar · View at Scopus
  24. I. Ericsson, L. G. Persson, T. Berglundh, T. Edlund, and J. Lindhe, “The effect of antimicrobial therapy on periimplantitis lesions: An experimental study in the dog,” Clinical Oral Implants Research, vol. 7, no. 2, pp. 320–328, 1996. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Esposito, J.-M. Hirsch, U. Lekholm, and P. Thomsen, “Biological factors contributing to failures of osseointegrated oral implants: (II). Etiopathogenesis,” European Journal of Oral Sciences, vol. 106, no. 3, pp. 721–764, 1998. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Addy and M. V. Martin, “Systemic antimicrobials in the treatment of chronic periodontal diseases: A dilemma,” Oral Diseases, vol. 9, no. 1, pp. 38–44, 2003. View at Publisher · View at Google Scholar · View at Scopus
  27. H. Löe and C. R. Schiott, “The effect of mouthrinses and topical application of chlorhexidine on the development of dental plaque and gingivitis in man,” Journal of Periodontal Research, vol. 5, no. 2, pp. 79–83, 1970. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Quirynen, W. Teughels, M. De Soete, and D. Van Steenberghe, “Topical antiseptics and antibiotics in the initial therapy of chronic adult periodontitis: Microbiological aspects,” Periodontology 2000, vol. 28, no. 1, pp. 72–90, 2002. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Faveri, L. C. Gursky, M. Feres, J. A. Shibli, S. L. Salvador, and L. C. De Figueiredo, “Scaling and root planing and chlorhexidine mouthrinses in the treatment of chronic periodontitis: A randomized, placebo-controlled clinical trial,” Journal of Clinical Periodontology, vol. 33, no. 11, pp. 819–828, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. O. Carcuac, I. Abrahamsson, G. Charalampakis, and T. Berglundh, “The effect of the local use of chlorhexidine in surgical treatment of experimental peri-implantitis in dogs,” Journal of Clinical Periodontology, vol. 42, no. 2, pp. 196–203, 2015. View at Publisher · View at Google Scholar · View at Scopus
  31. K. F. Schulz, D. G. Altman, and D. Moher, “CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials,” International Journal of Surgery, vol. 9, no. 8, pp. 672–677, 2011. View at Publisher · View at Google Scholar
  32. S. Annibali, I. Bignozzi, M. P. Cristalli, F. Graziani, G. La Monaca, and A. Polimeni, “Peri-implant marginal bone level: A systematic review and meta-analysis of studies comparing platform switching versus conventionally restored implants,” Journal of Clinical Periodontology, vol. 39, no. 11, pp. 1097–1113, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. P. Papaspyridakos, C.-J. Chen, M. Singh, H.-P. Weber, and G. O. Gallucci, “Success criteria in implant dentistry: a systematic review,” Journal of Dental Research, vol. 91, no. 3, pp. 242–248, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. H. De Bruyn, P. Bouvry, B. Collaert, C. De Clercq, G. R. Persson, and J. Cosyn, “Long-term clinical, microbiological, and radiographic outcomes of brånemark™ implants installed in augmented maxillary bone for fixed full-arch rehabilitation,” Clinical Implant Dentistry and Related Research, vol. 15, no. 1, pp. 73–82, 2013. View at Publisher · View at Google Scholar
  35. E. De Smet, R. Jacobs, F. Gijbels, and I. Naert, “The accuracy and reliability of radiographic methods for the assessment of marginal bone level around oral implants,” Dentomaxillofacial Radiology, vol. 31, no. 3, pp. 176–181, 2002. View at Publisher · View at Google Scholar · View at Scopus
  36. R. Caricasulo, L. Malchiodi, P. Ghensi, G. Fantozzi, and A. Cucchi, “The influence of implant-abutment connection to peri-implant bone loss: A systematic review and meta-analysis,” Clinical Implant Dentistry and Related Research, vol. 20, no. 4, pp. 653–664, 2018. View at Publisher · View at Google Scholar
  37. M. Esposito, L. Murray-Curtis, M. G. Grusovin, P. Coulthard, and H. V. Worthington, “Inter- ventions for replacing missing teeth: dif- ferent types of dental implants,” Cochrane Database of Systematic Reviews, Article ID D003815, 2007. View at Google Scholar
  38. A. M. Kielbassa, R. M. Fuentes, M. Goldstein et al., “Randomized controlled trial comparing a variable-thread novel tapered and a standard tapered implant: Interim one-year results,” The Journal of Prosthetic Dentistry, vol. 101, no. 5, pp. 293–305, 2009. View at Publisher · View at Google Scholar
  39. F. Pieri, N. N. Aldini, C. Marchetti, and G. Corinaldesi, “Influence of implant-abutment interface design on bone and soft tissue levels around immediately placed and restored single-tooth implants: A randomized controlled clinical trial,” The International Journal of Oral & Maxillofacial Implants, vol. 26, no. 1, pp. 169–178, 2011. View at Google Scholar · View at Scopus
  40. K.-T. Koo, E.-J. Lee, J.-Y. Kim et al., “The effect of internal versus external abutment connection modes on crestal bone changes around dental implants: A radiographic analysis,” Journal of Periodontology, vol. 83, no. 9, pp. 1104–1109, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Bateli, W. Att, and J. R. Strub, “Implant neck configurations for preservation of marginal bone level: a systematic review,” The International Journal of Oral & Maxillofacial Implants, vol. 26, no. 2, pp. 290–303, 2011. View at Google Scholar · View at Scopus
  42. A. Pozzi, E. Agliardi, M. Tallarico, and A. Barlattani, “Clinical and radiological outcomes of two implants with different prosthetic interfaces and neck configurations: Randomized, controlled, split-mouth clinical trial,” Clinical Implant Dentistry and Related Research, vol. 16, no. 1, pp. 96–106, 2014. View at Publisher · View at Google Scholar · View at Scopus
  43. T. Traini, M. Berardini, F. Congedi, B. Sinjari, P. Trisi, and S. Caputi, “Impact of second stage surgery on bone remodeling around new hybrid titanium implants: a prospective clinical study in humans,” Implant Dentistry, vol. 26, no. 1, pp. 121–128, 2017. View at Publisher · View at Google Scholar · View at Scopus
  44. B. Assenza, D. Tripodi, A. Scarano et al., “Bacterial leakage in implants with different implant-abutment connections: An in vitro study,” Journal of Periodontology, vol. 83, no. 4, pp. 491–497, 2012. View at Publisher · View at Google Scholar · View at Scopus
  45. B. Assenza, L. Artese, A. Scarano et al., “Screw vs cement-implant-retained restorations: an experimental study in the beagle. Part 2. Immunohistochemical evaluation of the peri-implant tissues.,” Journal of Oral Implantology, vol. 32, no. 1, pp. 1–7, 2006. View at Publisher · View at Google Scholar · View at Scopus
  46. F. H. Stancari, M. A. Rehder De Araujo, P. C. R. Conti et al., “Bone behavior in relation to the depth of the line of marginal cementation of prostheses on morse cone implants: Radiographic evaluation in a dog model,” Implant Dentistry, vol. 24, no. 6, pp. 720–725, 2015. View at Publisher · View at Google Scholar · View at Scopus
  47. R. Adell, U. Lekholm, B. Rockler, and P. I. Branemark, “A 15-year study of osseointegrated implants in the treatment of the edentulous jaw,” International Journal of Oral Surgery, vol. 10, no. 6, pp. 387–416, 1981. View at Publisher · View at Google Scholar · View at Scopus
  48. T. Jemt, U. Lekholm, and K. Gröndahl, “3-year followup study of early single implant restorations ad modum Brånemark,” The International journal of periodontics & restorative dentistry, vol. 10, no. 5, pp. 340–349, 1990. View at Google Scholar · View at Scopus
  49. J. F. Cox and G. A. Zarb, “The longitudinal clinical efficacy of osseointegrated dental implants: A 3-year report,” The International Journal of Oral & Maxillofacial Implants, vol. 2, no. 2, pp. 91–100, 1987. View at Google Scholar · View at Scopus
  50. J. S. Hermann, D. L. Cochran, P. V. Nummikoski, and D. Buser, “Crestal bone changes around titanium implants. A radiographic evaluation of unloaded nonsubmerged and submerged implants in the canine mandible,” Journal of Periodontology, vol. 68, no. 11, pp. 1117–1130, 1997. View at Publisher · View at Google Scholar · View at Scopus
  51. R. J. Lazzara and S. S. Porter, “Platform switching: a new concept in implant dentistry for controlling postrestorative crestal bone levels,” The International journal of periodontics & restorative dentistry, vol. 26, no. 1, pp. 9–17, 2006. View at Google Scholar · View at Scopus
  52. L. Canullo, M. Caneva, and M. Tallarico, “Ten-year hard and soft tissue results of a pilot double-blinded randomized controlled trial on immediately loaded post-extractive implants using platform-switching concept,” Clinical Oral Implants Research, vol. 28, pp. 1195–1203, 2016. View at Publisher · View at Google Scholar · View at Scopus
  53. Y.-T. Hsu, H.-L. Chan, I. Rudek et al., “Comparison of Clinical and radiographic outcomes of platform-switched implants with a rough collar and platform-matched implants with a smooth collar: A 1-year randomized clinical trial,” The International Journal of Oral & Maxillofacial Implants, vol. 31, no. 2, pp. 382–390, 2016. View at Google Scholar · View at Scopus
  54. G. E. Romanos, M. T. Biltucci, A. Kokaras, and B. J. Paster, “Bacterial Composition at the Implant-Abutment Connection under Loading in vivo,” Clinical Implant Dentistry and Related Research, vol. 18, no. 1, pp. 138–145, 2016. View at Publisher · View at Google Scholar · View at Scopus
  55. M. Paolantonio, G. Perinetti, S. D'Ercole et al., “Internal decontamination of dental implants: An in vivo randomized microbiologic 6-month trial on the effects of a chlorhexidine gel,” Journal of Periodontology, vol. 79, no. 8, pp. 1419–1425, 2008. View at Publisher · View at Google Scholar · View at Scopus
  56. Y. C. De Waal, G. M. Raghoebar, J. J. Huddleston Slater, H. J. Meijer, E. G. Winkel, and A. J. Van Winkelhoff, “Erratum: Implant decontamination during surgical peri-implantitis treatment: A randomized, double-blind, placebo-controlled trial,” Journal of Clinical Periodontology, vol. 40, no. 2, pp. 186–195, 2013. View at Google Scholar · View at Scopus
  57. F. Schwarz, N. Sahm, G. Iglhaut, and J. Becker, “Impact of the method of surface debridement and decontamination on the clinical outcome following combined surgical therapy of peri-implantitis: a randomized controlled clinical study,” Journal of Clinical Periodontology, vol. 38, no. 3, pp. 276–284, 2011. View at Publisher · View at Google Scholar · View at Scopus
  58. M. Y. H. Chin, A. Sandham, J. de Vries, H. C. van der Mei, and H. J. Busscher, “Biofilm formation on surface characterized micro-implants for skeletal anchorage in orthodontics,” Biomaterials, vol. 28, no. 11, pp. 2032–2040, 2007. View at Publisher · View at Google Scholar · View at Scopus