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BioMed Research International
Volume 2018, Article ID 5429868, 7 pages
Research Article

Preliminary Exploration of Epidemiologic and Hemodynamic Characteristics of Restrictive Filling Diastolic Dysfunction Based on Echocardiography in Critically Ill Patients: A Retrospective Study

1Department of Critical Care Medicine, West China Hospital of Sichuan University, 37 Guoxue Avenue, Chengdu 610041, China
2Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
3Department of Critical Care Medicine, The First Hospital of Tsinghua University, Beijing 100016, China
4Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China

Correspondence should be addressed to Yan Kang; moc.361@321_nay_gnak

Received 3 October 2017; Revised 7 January 2018; Accepted 15 January 2018; Published 21 February 2018

Academic Editor: Gianluca Pontone

Copyright © 2018 Yi Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To preliminarily describe the epidemiologic and hemodynamic characteristics of critically ill patients with restrictive filling diastolic dysfunction based on echocardiography. Setting. A retrospective study. Methods. Epidemiologic characteristics of patients with restrictive filling diastolic dysfunction in ICU were described; clinical and hemodynamic data were preliminarily summarized and compared between patients with and without restrictive filling diastolic dysfunction; most of the data were based on echocardiography. Results. More than half of the patients in ICU had diastolic dysfunction and about 16% of them had restrictive filling pattern. The patients who had restrictive filling diastolic dysfunction were more likely to have wider diameter of IVC ( versus , ), higher extravascular lung water score ( versus , ), lower left ventricular ejection fraction (EF-S: versus , ), and lower percentage of normal LAP that was estimated by E/e′ (8.9% versus 90.0%, ) when compared with those of patients without restrictive filling diastolic dysfunction. Conclusion. Our results suggest that critically ill patients with restrictive filling diastolic dysfunction may experience rising volume status, increasing extravascular lung water ultrasonic score, reducing long-axis systolic dysfunction, and less possibility of normal left atrial pressure. Intensivists are advised to pay more attention to patients with diastolic dysfunction, especially the exquisite fluid management of patients with restrictive filling pattern due to the close relationship of restrictive filling diastolic dysfunction with volume status and extravascular lung water in our study.