SRMDAP: SimRank and Density-Based Clustering Recommender Model for miRNA-Disease Association Prediction

Figure 1

Illustration of the process of constructing miRNA and disease similarity network and predicting miRNA-disease associations. (a) A simple example of constructing similarity of miRNAs 1 and 2 is shown in (a). (b) A simple example of constructing similarity of diseases 1 and 2 is shown in (b). (c) The known miRNA-disease associations. (d) Predicting miRNA-disease associations through density-based recommender model by integrating miRNA similarity network, disease similarity network, and the known miRNA-disease associations.