BioMed Research International / 2018 / Article / Fig 5

Research Article

Protective Effects of Silymarin and Silibinin against DNA Damage in Human Blood Cells

Figure 5

Schematic representation of the effects of silymarin and silibinin on chemopreventive mechanisms. While methyl methanesulfonate (MMS) is highly associated with enhanced reactive oxygen species (ROS) production [14] and apoptotic response [15], silymarin (SM) and silibinin (SB) exhibit strong antioxidant activities [5, 16] and can prevent apoptosis and influence the genomic stability and the DNA repair system.

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