The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin

Figure 5

Plasma antibody titers after different immunization stages. (a) Anti-TT IgG titers in plasma from group 1-6; (b) anti-TeNT-Hc IgG titers in plasma; (c) anti-TT IgG titers in plasma after three stages immunization and TT routine immunized plasma; (d) anti-TeNT-Hc IgG titers in plasma after three stages immunization and TT routine immunized plasma. Unpaired two-tailed Student’s t-test was used to determine the significance of the differences in antibody titers between the groups. P values ≤ 0.05 were considered to be significant. P<0.01 was considered to be very significant and marked as .

(a)

(b)

(c)

(d)