Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals

Table 5

Genotypes and allelic frequencies of NLRP3 SNPs in MES(+) and MES(−) groups.

SNP site	MES(+); (%)	MES(−); (%)	value	OR	95% CI
rs4612666
genotype
CC	12 (15.8%)	51 (23.5%)	-	1
CT	38 (50.0%)	125 (57.6%)	0.464	1.314	0.633–2.730
TT	26 (34.2%)	41 (18.9%)	0.015	2.706	1.210–6.048
allele
C	62 (40.8%)	227 (52.3%)	-	1
T	90 (59.2%)	207 (47.7%)	0.015	1.593	1.095–2.315
rs10754558
genotype
CC	18 (23.7%)	55 (25.3%)	-	1
CG	42 (55.3%)	112 (51.6%)	0.624	1.175	0.617–2.237
GG	16 (21.1%)	50 (23.0%)	0.841	1.084	0.494–2.378
allele
C	78 (51.3%)	222 (51.2%)	-	1
G	74 (48.7%)	212 (48.8%)	0.972	0.993	0.687–1.438
rs7512998
genotype
CC	1 (1.3%)	1 (0.5%)	-	1
CT	15 (19.75%)	30 (13.8%)	0.521	0.388	0.022–6.999
TT	60 (78.95%)	186 (85.7%)	0.318	0.234	0.014–4.047
allele
C	17 (11.2%)	32 (0.074)	-	1
T	135 (88.8%)	402 (0.926)	0.144	0.632	0.340–1.175