Simvastatin Effects on Inflammation and Platelet Activation Markers in Hypercholesterolemia

Figure 2

Box-plot analysis of the platelet activation markers soluble P-selectin (sP-selectin), Rantes, soluble CD-40 ligand (sCD-40L), and platelet-derived growth factor (PDGF)-BB, in hypercholesterolemic patients assigned to diet alone (Control) or to diet plus simvastatin (Simva) at baseline (pre) and after a two-month follow-up (post). Significance of intragroup differences was estimated by paired t-test or Wilcoxon test, as appropriate. Solid lines: median values; boxes: interquartile range; whiskers: nonoutlier range; closed circles: outliers.