Detecting Early Warning Signal of Influenza A Disease Using Sample-Specific Dynamical Network Biomarkers

Figure 2

The early warning index of influenza disease. In all the figures, the abscissa represents the time point t. (a) The average coefficient variation (CV) of genes expression in DNB at 10 time points. (b) The average difference in absolute value between genes expression inside DNB and any other outside DNB (ODIF) at 10 time points. (c) The average difference (DIF) in absolute value of genes expression in DNB at 10 time points. (d) The early warning index (EWI) of the case set of high-throughput experimental data for influenza A disease.

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