Clinically Symptomatic Pericardial Effusions in Hospitalized Systemic Sclerosis Patients: Demographics and Management

Table 2

Individual clinical characteristics of SSc patients with pericardial disease.

Patient	Age	Type of SSc	Diagnosis	Overlap syndrome	Size of pericardial effusion	Presence of tamponade	Right heart failure	Procedure	Fluid study	Meds prior to admission
1	60	Unknown			M-L	-	Severe
2	71	Limited		+ (PM, MCTD)	M	-	Mild	Thoracentesis	Pleural fluid: transudative (LDH 88, Pr 1.3, NUC 63, seg 52)
3	60	Unknown			L	-	Severe			Iloprost, sildenafil, bosentan, and plaquenil
4	68	Unknown			M-L	-
5	62	Limited	New		M-L	+	Severe
6	61	Diffuse			M-L	-				Methylprednisolone
7	55	Limited			M	-	Mild			Treprostinil, macitentan, sildenafil
8	65	Unknown			S	-				Mycophenolate, tacrolimus, and prednisone
9	79	Unknown			L	-	Severe
10	66	Limited	28 yrs		M	-				Ambrisentan, nifedipine
11	57	Unknown			M	-				Nifedipine
12	49	Unknown			M	-
13	72	Unknown	New		M	-	Moderate			Nifedipine, ibuprofen
14	59	Unknown	New	+ (IBM)	M-L	-
15	63	Limited	2 yrs	+ (Sicca)	M	-	Severe			Cevimeline, candesartan
16	58	Unknown	13 yrs		L	-	Moderate			Ambrisentan, sildenafil, iloprost, and mycophenolate
17	57	Unknown	14 yrs		M-L	+	Severe	Thoracentesis		Macitentan, mycophenolate, and sildenafil
18	56	Limited			L	+	Mod-severe			Sildenafil
19	56	Diffuse	2 mo		L	-		Pericardiocentesis	WBC 178, RBC 9, GS neg, Cx neg, cytology neg	Methotrexate, prednisone
20	48	Diffuse	8 yrs	+ (MCTD)	L	-		Pericardiocentesis → pericardial window	WBC 240, RBC 3550, pleural fluid: no malignancy, reactive mesothelial cells, and chronic inflammation	Lisinopril
21	44	Diffuse	New		L	-		Pericardiocentesis → pericardial window	Cytology neg, AFB neg
22	66	Diffuse	New		L	+		Pericardiocentesis → pericardial window	WBC 568, RBC 815, GS neg, and cytology neg	Prednisone
23	45	Diffuse	7 mo	+ (RA, Sjogren, DM)	M	-		Pericardial window		Methotrexate, plaquenil

S = small, M = moderate, L = large, PM = polymyositis, IBM = inclusion body myositis, MCTD = mixed connective tissue disease, RA = rheumatoid arthritis, and DM = dermatomyositis.