Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects

Figure 1

Metabolic pathway of propofol and fospropofol. Dashed arrows represent minor routes and both metabolites can undergo glucuronide and sulfate conjugation. SULT: sulfotransferase; UGT: UDP-glucuronosyltransferase; ALDH: aldehyde dehydrogenase; ALP: alkaline phosphatase; NQO1: diaphorase; CYP: cytochrome P450.