Research Article

A Sargassum fluitans Borgesen Ethanol Extract Exhibits a Hepatoprotective Effect In Vivo in Acute and Chronic Liver Damage Models

Table 1

Effect of S. fluitans ethanol extract on relative liver weight (RLW), ALT, and AST serum activities in five groups of an acute liver damage model in mice. Results are expressed as means ± SD (n = 4). p-Values: vs. APAP; vs. control; vs. APAP; vs. control, according to one-way ANOVA with a Tukey post hoc test.

GroupsRLW ALT (U/L)AST (U/L)

1. Control8.37 ± 0.3644.75 ± 0.4168.25 ± 0.73
2. EE8.41 ± 0.2344.87 ± 0.6569.54 ± 0.86
3. APAP9.21± 0.14199.50 ± 0.52472.50 ± 0.58
4. NAC + APAP8.39± 0.32&85.75 ± 0.76311.50 ± 0.49
5. EE + APAP8.48± 0.13&123.00 ± 0.43357.00 ± 0.77