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BioMed Research International
Volume 2018, Article ID 7290913, 6 pages
Review Article

Saliva as a Future Field in Psoriasis Research

1Department of Biomedical, Surgical & Dental Sciences, University of Milan, 20122 Milan, Italy
2Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy
3Clinical Dermatology, Department of Biomedical, Surgical and Dental Sciences, IRCCS Galeazzi Orthopaedic Institute, University of Milan, 20126 Milan, Italy
4Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita’ degli Studi di Milano, Unita’ Operativa di Dermatologia, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milano, Italy
5Center for Jawbone Atrophies Policlinico Hospital, University of Milan School of Dentistry, 20122 Milan, Italy
6Young Dermatologists Italian Network (YDIN), GISED, 24122 Bergamo, Italy

Correspondence should be addressed to Giovanni Damiani; moc.liamg@inaimad.innavoig.rd

Received 31 January 2018; Accepted 11 April 2018; Published 20 May 2018

Academic Editor: Fernando C. e Silva

Copyright © 2018 Farah Asa’ad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Psoriasis is a skin inflammatory disease characterized by an increased body of comorbidities, including parodontopathy. Despite the visibility of skin lesions, prognostic biomarkers, related to disease monitoring and therapeutic effectiveness, are still missing. Although several markers have been studied, none of them has been identified as an independent prognostic factor. This concise review aims to summarize the current knowledge and results in saliva research applied to psoriasis. Combination of different markers could improve the prognostic prediction in patients with psoriasis. Future studies are needed to implement research on salivary biomarkers and their prognostic/therapeutic effects in the management of patients with psoriasis.