MicroRNA Expression Profiling in Psoriatic Arthritis

Figure 2

Pathway enrichment analysis for deregulated miRNAs in PsA. (a) Histograms representing enrichment values for selected KEGG pathways obtained by DIANA-miRPath v.3 software analysis. Functional analyses were conducted for the PsA only active, PsA only nonactive, and PsA common miRNA list. Overrepresentation statistical analysis was performed for the union of targeted genes by miRNA lists (“Genes Union” option) based on TARBASE 7.0. (b) Enrichment analysis comparison between miRNA subsets for the KEGG pathway “proteoglycans in cancer.” Enrichment value, number of genes targeted (#genes), and number of miRNAs (#miRNAs) for each subset are shown.

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