Dynamic Changes in Plasma MicroRNAs Have Potential Predictive Values in Monitoring Recurrence and Metastasis of Nasopharyngeal Carcinoma

Figure 2

Dynamic changes in plasma miRNAs levels between pre- and posttreatment. (a) Levels of eight plasma miRNAs were examined in the paired samples of pretreatment and 3-month posttreatment of 90 patients compared with 35 healthy controls. The levels of five plasma miRNAs (miR-9-3p, miR-124-3p, miR-892b, miR-3135a, and miR-3676-3p) were significantly dysregulated and showed a tendency to go back to basic normal levels at 3-month posttreatment. (b–f) Dynamic changes in five plasma miRNA levels at three time points after treatment. Repeated-measure analysis of variance (ANOVA) was used to analyze the differences before treatment and 3, 6, and 12 months after treatment. ; .

(a)

(b)

(c)

(d)

(e)

(f)