Low Platelet to White Blood Cell Ratio Indicates Poor Prognosis for Acute-On-Chronic Liver Failure

Table 1

Clinical characteristics of studied subjects.

	Healthy controls; ( = 97)	ACLF; ( = 433)
Age (year)	40 ± 11.7	42 ± 11.44	0.123
Gender (male/female)	72/25	360/73	0.059
White blood cell count (×10^9/L)	5.86 ± 1.53	7.72 ± 4.06	<0.001
Blood platelet (×10^9/L)	228 ± 52.54	111 ± 64.55	<0.001
PWR	39.16 ± 9.80	14.03 ± 7.15	<0.001
International normalized ratio (INR)	0.98 ± 0.52	2.58 ± 1.09	<0.001
Alanine aminotransferase (U/L)	20 ± 12.8	361 ± 848.14	<0.001
Aspartate aminotransferase (U/L)	20 ± 5.6	204 ± 668.87	<0.001
Total bilirubin (μmol/L)	13.23 ± 4.95	369.4 ± 165.51	<0.001
Albumin (g/L)	47.3 ± 2.23	31.7 ± 13.80	<0.001
HBV DNA level (log IU/ml)		4.87 ± 2.14
Mortality	0	129	<0.001