Review Article
Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery: An Update Meta-Analysis and Trial Sequential Analysis
Table 2
Secondary endpoints after randomizations.
| Secondary outcomes | Number of studies | 95% CI | (heterogeneity) | (%) | (overall effect) |
| Cardiac index (L/min/m2) | 7 | 0.66 [0.62, 0.70] | <0.00001 | 89 | <0.00001 | Pulmonary capillary wedge pressure (mmHg) | 7 | −2.35 [−2.78, −1.93] | 0.001 | 73 | <0.00001 | Postoperative atrial fibrillation | 11 | 0.97 [0.85, 1.09] | 0.0006 | 68 | 0.60 | Postoperative renal replacement therapy | 8 | 0.51 [0.33, 0.77] | 0.86 | 0 | 0.002 | Length of ICU stay (days) | 10 | −0.48 [−0.72, −0.24] | <0.00001 | 85 | <0.0001 |
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