Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery: An Update Meta-Analysis and Trial Sequential Analysis

Table 3

Stratified analyses of levosimendan administration and surgical type.

Group	Number of studies	95% CI	(heterogeneity)	(%)	(overall effect)
Timing and dose of infusion of levosimendan
Bolus + 24-hour prolonged infusion	7	0.48 [0.32, 0.73]	0.62	0	0.0004
No bolus + 24-hour prolonged infusion	5	0.79 [0.41, 1.53]	0.43	0	0.49
No bolus + unclear duration	3	0.35 [0.13, 1.00]	0.72	0	0.05
Type of cardiac surgery
Coronary surgery	10	0.56 [0.35, 0.90]	0.58	0	0.02
Other cardiac surgeries	5	0.50 [0.32, 0.78]	0.47	0	0.002