Research Article
Blood Lactate or Lactate Clearance: Which Is Robust to Predict the Neurological Outcomes after Cardiac Arrest? A Systematic Review and Meta-Analysis
Table 2
Subgroup analysis of lactate on admission and neurological outcomes.
| Subgroups | No. of study | WMD | 95CI | P for heterogeneity | I2 () |
| Age | | | | | | Adult | 14 | -2.27 | -2.94, -1.69 | 0.000 | 80.2 | Old people | 8 | -3.17 | -4.26, -1.60 | 0.000 | 87.5 | CA Location | | | | | | OHCA | 18 | -2.79 | -3.65, -1.93 | 0.000 | 89.5 | OHCA/IHCA | 4 | -1.93 | -2.82, -1.04 | 0.004 | 77.1 | Outcome follow up time | | | | | | Short-term (< 1m) | 18 | -2.52 | -3.20, -1.84 | 0.000 | 84.5 | Long-term (≥ 3 m) | 4 | -3.10 | -5.04, -1.16 | 0.000 | 94.2 | Study quality | | | | | | Intermediate (≤6) | 8 | -2.88 | -4.12, -1.64 | 0.000 | 77.2 | High (>6) | 14 | -2.56 | -3.48, -1.64 | 0.000 | 93.6 | Data transformation | | | | | | Yes | 15 | -3.00 | -3.84, -2.16 | 0.000 | 86.4 | No | 7 | -1.53 | -2.09, -0.97 | 0.03 | 56.9 | Initial shockable rhythm | | | | | | Low percentage (<50%) | 13 | -2.83 | -3.80, -1.87 | 0.000 | 94.2 | High percentage (≥50%) | 9 | -2.28 | -3.28, -1.29 | 0.001 | 68.1 | Study design | | | | | | Retrospective | 13 | -1.92 | -2.50, -1.35 | 0.000 | 81.2 | Prospective | 9 | -4.47 | -4.86, -4.08 | 0.432 | 0.2 |
|
|