TY - JOUR
A2 - Bach, Horacio
AU - Loiseau, Clémence
AU - Portier, Emilie
AU - Corre, Marie-Hélène
AU - Schlusselhuber, Margot
AU - Depayras, Ségolène
AU - Berjeaud, Jean-Marc
AU - Verdon, Julien
PY - 2018
DA - 2018/10/22
TI - Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti-Legionella Agents
SP - 8194368
VL - 2018
AB - Legionella pneumophila, the causative agent of Legionnaires’ disease, is a waterborne bacterium mainly found in man-made water systems in close association with free-living amoebae and multispecies biofilms. Pseudomonas strains, originating from various environments including freshwater systems or isolated from hospitalized patients, were tested for their antagonistic activity towards L. pneumophila. A high amount of tested strains was thus found to be active. This antibacterial activity was correlated to the presence of tensioactive agents in culture supernatants. As Pseudomonas strains were known to produce biosurfactants, these compounds were specifically extracted and purified from active strains and further characterized using reverse-phase HPLC and mass spectrometry methods. Finally, all biosurfactants tested (lipopeptides and rhamnolipids) were found active and this activity was shown to be higher towards Legionella strains compared to various other bacteria. Therefore, described biosurfactants are potent anti-Legionella agents that could be used in the water treatment industry although tests are needed to evaluate how effective they would be under field conditions.
SN - 2314-6133
UR - https://doi.org/10.1155/2018/8194368
DO - 10.1155/2018/8194368
JF - BioMed Research International
PB - Hindawi
KW -
ER -