Antidepressant Effect of Fraxinus rhynchophylla Hance Extract in a Mouse Model of Chronic Stress-Induced Depression

Figure 1

Effect of FX extract on body weight and depressive-like behavior. (a) Experimental procedure schematic. (b) Body weight in all mice groups as a % of baseline body weight (n = 8-10). (c1) Representative recordings of total distance travelled in Open Field Test in all groups. (c2) Differences between the total distances travelled in center (n = 8-9). (c3) Differences between mean numbers of entries into center in all groups (n = 8). (d) Mean immobility time between groups in the Forced Swim Test (n = 11). Mean ± SD. P < 0.01 and P < 0.0001 versus normal group; P < 0.05, P < 0.01, and P < 0.001 versus control group.